Glycine (Gly) – DM6 Health


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Glycine (Gly)


What is glycine and what is it used for in the body?

Glycine is an amino acid that is involved in various physiological processes in the body. It is a non-essential amino acid, meaning that it can be synthesized by the body and does not need to be obtained through the diet. Glycine is involved in the synthesis of proteins, the metabolism of fats, and the regulation of the immune system. It is also a neurotransmitter, and is involved in the transmission of nerve impulses in the brain.

How is glycine measured in the body?

Glycine can be measured in the body through various laboratory tests, including blood tests and urine tests. In blood tests, glycine levels are typically measured in the plasma, which is the liquid portion of the blood. In urine tests, glycine is usually measured as a breakdown product called glycolic acid.

What is the normal range for glycine levels in the body?

The normal range for glycine levels in the body varies depending on the method used to measure it and the specific laboratory that performs the test. In general, normal glycine levels in the plasma are typically between 50 and 350 micromoles per liter (μmol/L). In urine, normal glycine levels are typically between 30 and 200 millimoles per liter (mmol/L).

What can cause abnormal glycine levels in the body?

Abnormal glycine levels in the body can be caused by a variety of factors, including medical conditions such as malnutrition, liver disease, and kidney failure. In addition, certain medications, such as aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs), can affect glycine levels in the body.

How is glycine related to the diagnosis and treatment of liver disease?

Glycine levels can be measured as part of the diagnostic process for liver disease. Abnormal glycine levels in the plasma may be indicative of liver damage or dysfunction. In addition, glycine has been shown to have protective effects on the liver and is often used as a supplement in the treatment of liver disease.

How is glycine related to the treatment of schizophrenia?

Glycine has been shown to have antipsychotic effects and is sometimes used as an adjunctive treatment for schizophrenia. It is thought to work by modulating the activity of the neurotransmitter dopamine in the brain.

Are there any potential side effects associated with glycine supplements?

Glycine supplements are generally considered safe, with few reported side effects. However, some people may experience gastrointestinal side effects such as nausea, bloating, or diarrhea when taking high doses of glycine. It is important to consult a healthcare provider before starting any supplement regimen.


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"Glycine." University of Maryland Medical Center, University of Maryland Medical System,

"Glycine and Schizophrenia: A Review." American Journal of Psychiatry, vol. 156, no. 7, 1999, pp. 1130-1135., doi:10.1176/ajp.156.7.1130