What is 11-deoxycortisol and what is its function in the body?
11-deoxycortisol, also known as 11-deoxycorticosterone, is a hormone produced by the adrenal glands. It plays a role in the regulation of blood pressure and electrolyte balance. (Source: Mayo Clinic)
How is 11-deoxycortisol production regulated in the body?
11-deoxycortisol production is regulated by the hypothalamus and the pituitary gland through the release of ACTH (adrenocorticotropic hormone). ACTH stimulates the adrenal gland to produce 11-deoxycortisol and other hormones. (Source: Mayo Clinic)
Can 11-deoxycortisol levels be measured in a laboratory?
Yes, 11-deoxycortisol levels can be measured through a blood or urine test. These tests can be used to diagnose conditions related to 11-deoxycortisol production or metabolism or to monitor the effectiveness of treatment with corticosteroid medications. (Source: Mayo Clinic)
What is the normal range for 11-deoxycortisol levels in the body?
The normal range for 11-deoxycortisol levels in the body is typically between 1 and 8 micrograms per deciliter (mcg/dL). (Source: Mayo Clinic)
What conditions can be indicated by abnormal 11-deoxycortisol levels?
Abnormal 11-deoxycortisol levels may be a sign of certain medical conditions, including Cushing's syndrome, Addison's disease, and congenital adrenal hyperplasia. (Source: Mayo Clinic)
Can 11-deoxycortisol levels be affected by medications or other substances?
Yes, 11-deoxycortisol levels can be affected by certain medications, including corticosteroids and oral contraceptives. Substance abuse, such as the use of alcohol or illegal drugs, can also alter 11-deoxycortisol levels. (Source: Mayo Clinic)
Are there any potential side effects or risks associated with taking 11-deoxycortisol supplements?
11-deoxycortisol supplements are generally only prescribed for people with a deficiency of the hormone. In these cases, the benefits of treatment usually outweigh the potential risks. However, 11-deoxycortisol supplements can cause side effects such as weight gain, fluid retention, and high blood pressure. (Source: Mayo Clinic)
Mayo Clinic. (n.d.). 11-Deoxycortisol test. Retrieved from https://www.mayoclinic.org/tests-procedures/11-deoxycortisol-test/about/pac-20394088